Take the test and discover your Y-Score

The “Y-Score Test” tool is provided for information purposes only and it is not intended to be a substitute for professional advice.

The method used for the Y-Score Test is a simplification of the Y-mpact methodology internally developed by Ysios, and its results are not certified or guaranteed in any way. Ysios makes no representations or warranties of any kind, express or implied, about the completeness, accuracy, reliability, or suitability of the tool.

Social Impact

Here we assess the overall impact that the disease/condition has on society

Q1. What is the disease’s incidence (defined as newly diagnosed patients per year)?

More than 5 million

Between 1 million and 5 million

Between 500 thousand and 1 million

Between 100 thousand and 500 thousand

Between 10 thousand and 100 thousand

Less than 10 thousand

I don't know

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Q2. What is the disease’s prevalence (defined as number of patients alive today)?

More than 10 million

Between 5 million and 10 million

Between 1 million and 5 million

Between 500 thousand and 1 million

Between 100 thousand and 500 thousand

Less than 100 thousand

I don't know

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Q3. Is the disease most often associated with children?

Yes

No

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Q4. Could the disease be considered one that primarily affects individuals living in the developing world, developed world, or is it global?

Developing world

Developed world

Global

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Q5. What is the 5-year mortality rate of the disease?

Above 80%

Between 60-80%

Between 40-60%

Between 20-40%

Less than 20%

I don't know

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Q6. What is the 10-year mortality rate of the disease?

Above 80%

Between 60-80%

Between 40-60%

Between 20-40%

Less than 20%

I don't know

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Q7. What is the disease’s severity?

Severe Chronic

Moderate Chronic

Severe Acute

Moderate Acute

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Q8. What is the economic impact of the disease?

High

Moderate

Low

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Innovation Impact

Here we assess the impact of the therapeutic product being developed

Q9. Is there a drug approved already to treat this disease with some effectiveness?

Yes

No

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Q10. Is there a drug approved already that cures the disease?

Yes

No

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Q11. Indicate the type of innovation that this drug represents

A new chemical/biological entity with a novel mechanism of action

An existing chemical/biological entity with a novel mechanism of action

A new chemical/biological entity with an existing mechanism of action

An existing chemical/biological entity with an existing mechanism of action

A reformulation/mashup

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Q12. What would the therapeutic product be considered?

A treatment

A cure

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Q13. Compared to other treatments available, how does the therapeutic product increase or decrease side effects?

Significantly reduces side effects

Reduces side effects

Worsens side effects

Significantly worsens side effects

Does not reduce nor worsen side effects

There is no treatment/cure available

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Q14. Compared to other treatments available, how would the therapeutic product change the cost of treatment?

It would significantly reduce the cost of treatment

It would reduce the cost of treatment

It would increase the cost of treatment

It would significantly increase the cost of treatment

It would not increase nor decrease the cost of treatment

There is no treatment/cure available

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Q15. What is the current stage of development of the therapeutic product?

Preclinical data available

Phase 1 data available

Phase 2 data available

Phase 3 data available

Marketed product

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Q16. Identify the disease category

This is a required field, choose an option

Q17. Is the drug considered an orphan drug?

Yes

No

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Q18. Does any literature exist on the biological target on which the drug exerts its mechanism of action?

There is existing literature

There is little literature

There is very little literature

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Governance Impact

Here we assess the impact related to the structure of the company and exit possibilities

Q19. Is it the first time that the CEO of the company holds the CEO position?

Yes

No

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Q20. What is the level of diversity of the executive team?

Very diverse

Diverse

Lacking diversity

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Q21. Please indicate the three pharmaceutical corporations most likely to acquire your company

This is a required field, choose three options

Q22. Indicate the likely pricing model that the company will have on market entry

Good pricing with access to all

Moderate pricing, with relatively easy access

High pricing, with restricted access

This is a required field, choose an option

Your Y-Score is

Social Impact

Innovation Impact

Governance Impact

Y-Score	Significance
	Very high impact
	High impact
	Good impact
	Some impact
	Low impact